An mRNA-based FimH nanoparticle vaccine against uropathogenic Escherichia coli is highly immunogenic in rodents

20251 citationsJournal Articlegold Open Access

Authors

Sandro Roier · CureVac (Germany)

Roberto Adamo

Roberto Rosini

Alfredo Pezzicoli

Maria Scarselli

Benjamin Petsch · CureVac (Germany)

Edith Jasny · CureVac (Germany)

Susanne Rauch · CureVac (Germany)

Abstract

The mRNA vaccine FimH<sub>DG</sub>-Ferritin with N1mΨ-modified nucleosides is a promising candidate for further development as a vaccine against UPEC.

Topics & Keywords

Escherichia coli research studies Immunotherapy and Immune Responses Bacterial Infections and Vaccines

Publication Details

Published in: Frontiers in Immunology

Volume 16, pp. 1668937-1668937

DOI: 10.3389/fimmu.2025.1668937

Field-Weighted Citation Impact: 1.87

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An mRNA-based FimH nanoparticle vaccine against uropathogenic Escherichia coli is highly immunogenic in rodents

Authors

Abstract

Topics & Keywords

Publication Details