Clinical outcomes and genomic alterations in patients with metastatic malignant phyllodes tumors

20250 citationsJournal Article

Authors

Aya Takigawa · National Kyushu Medical Center

Kenji Tsuchihashi · Kyushu University Hospital

Kenta Nio · Kyushu University Hospital

Koji Ide · Kyushu University

Wataru Kusano · Kyushu University

Yasuhiro Doi · National Kyushu Medical Center

Hirofumi Ohmura ·

Abstract

AI therapy is useful for advanced or recurrent MPTs. The observed clinical benefit of pazopanib in a patient with FGFR1 N546K-mutated MPT suggests that FGFR1 kinase domain mutations may be a relevant factor in responsiveness of FGFR1-targeted therapy. Further data accumulation is warranted.

Topics & Keywords

Fibroblast Growth Factor Research Breast Lesions and Carcinomas Gastrointestinal Tumor Research and Treatment

Publication Details

Published in: Japanese Journal of Clinical Oncology

Volume 56, Issue 2, pp. 139-147

DOI: 10.1093/jjco/hyaf169

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Clinical outcomes and genomic alterations in patients with metastatic malignant phyllodes tumors

Authors

Abstract

Topics & Keywords

Publication Details