Predicting, advancing, and rescuing human life-history strategies and sustainability from extrinsic mortality in extreme-Earth and extra-Earth niches

Harsh extreme-Earth and extra-Earth mortality sources pressure countervailing shifts in human life-history traits and survival-reproductive strategies, trading shorter lifespans and reproduction spans to hedge scarce gametes with sex-chromosome resilience. Darwinian trajectories for genotypes and phenotypes nonetheless remain unknown for future Earth-population sustainability and deep-space colonization. Controversial technology-assisted human evolution may be needed to narrow anthropological evolutionary-medicine disparities and prevent Humanity's extinction.