466 Streamlining precision oncology through EHR integration: Early lessons from a virtual forum

Abstract Introduction/Objective Integrating biomarker testing into electronic health record (EHR) systems offers operational and clinical benefits—from faster turnaround to improved access to genomic data for personalized care. Yet many cancer programs, especially in community settings, face challenges such as limited interoperability and siloed communication between pathology, oncology, and external labs depending on who places orders. To offer real-world solutions, the Association of Cancer Care Centers (ACCC) launched a national learning collaborative. Methods/Case Report ACCC, with guidance from an expert committee, designed a four-session virtual learning collaborative (February-June 2025) to advance EHR integration for biomarker testing. Sessions included three expert-led case studies and interactive breakout discussions. Participants were recruited via an interest form and shared feedback through post-session evaluations. Self-reported roles were standardized, and thematic analysis was used to identify key insights. Results: Conclusion Participants (n = 98) represented 27 states and diverse roles—primarily administrators (32%), clinicians (26%), and IT/EHR build staff (15%). Community cancer programs were the largest group of participants (42%), underscoring a clear need in this setting for improved EHR integration and peer learning. Survey themes revealed a strong interest in peer-shared workflows, collaborative resource-building to streamline internal processes (eg, reflex testing), and expanded skill-building and industry engagement opportunities within this collaborative format. These findings highlight a considerable need for an ongoing network of providers, clinical pathologists, and external lab professionals to exchange insights, evaluate vendor evaluation tools, and co-develop tools that support biomarker test integration. Such collaboration could accelerate workflow improvements, enhance guideline-concordant care delivery, and help build the infrastructure needed to advance precision oncology, particularly in community settings.