Diagnostic accuracy of the Cepheid MTB host response assay for the detection of pulmonary TB

20250 citationsJournal Articlediamond Open Access

Authors

Yosra Alkabab · Medical University of South Carolina

Yasha Rani · Frontier Science & Technology Research Foundation

Mohammed Farhad · Frontier Science & Technology Research Foundation

Carlos Zamudio · Universidad Peruana Cayetano Heredia

Tatiana Cáceres · Universidad Peruana Cayetano Heredia

Helen Cox · University of Cape Town

Wentzel Dowling

Abstract

The Xpert HR TB assay demonstrated promising sensitivity, but its specificity did not meet minimum target product profiles for a TB triage or case detection test. In its current form, Xpert HR cannot replace more sensitive nucleic acid amplification tests in sputum-productive individuals.

Topics & Keywords

Tuberculosis Research and Epidemiology Diagnosis and treatment of tuberculosis Infectious Diseases and Tuberculosis

Publication Details

Published in: IJTLD OPEN

Volume 2, Issue 11, pp. 646-654

DOI: 10.5588/ijtldopen.25.0380

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Diagnostic accuracy of the Cepheid MTB host response assay for the detection of pulmonary TB

Authors

Abstract

Topics & Keywords

Publication Details