Cognitive stagnation and executive function deficits in young children with <scp> <i>SCN1A</i> </scp> + Dravet syndrome: Detailed characterization of onset, progression, and impact in the <scp>ENVISION</scp> natural history study

20251 citationsJournal Articlehybrid Open Access

Authors

Joseph Sullivan · University of California, San Francisco

Μ. Scott Perry · Cook Children's Medical Center

Ingrid E. Scheffer · Royal Children's Hospital

James W. Wheless · Le Bonheur Children's Hospital

Susana Boronat · Hospital de Sant Pau

Andreas Brunklaus · University of Glasgow

Linda Laux

Abstract

Infants and young children with SCN1A+ DS show significant and progressive developmental slowing across several domains, highlighting urgent need for therapies to mitigate the devastating impact on individuals and families.

Topics & Keywords

Fetal and Pediatric Neurological Disorders Epilepsy research and treatment Congenital Heart Disease Studies

Publication Details

Published in: Epilepsia

Volume 67, Issue 3, pp. 1284-1302

DOI: 10.1111/epi.70015

Field-Weighted Citation Impact: 3.50

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Cognitive stagnation and executive function deficits in young children with <scp> <i>SCN1A</i> </scp> + Dravet syndrome: Detailed characterization of onset, progression, and impact in the <scp>ENVISION</scp> natural history study

Authors

Abstract

Topics & Keywords

Publication Details