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Objective: To evaluate the attitudes of family physicians in Lithuania toward the colorectal cancer (CRC) screening program, including their assessment of the program's importance, organization, accessibility, and implementation.Materials and Methods: A cross-sectional quantitative study was conducted between September and November 2024, involving an anonymous survey of 215 family physicians from various healthcare institutions in Lithuania. Data were collected using a structured 16-item questionnaire. Statistical analysis was performed using SPSS 29.0 and Excel 365, applying descriptive statistics and chi-square (χ²) tests, with a significance level of p ≤ 0.05.Results: 77.2% of respondents evaluated the program’s implementation favorably. Responsibility for program execution was most commonly attributed to themselves (85.6%) and nurses (83.3%). Patients were most frequently invited to participate verbally during consultations (96.3%) or by phone (74%). The most influential factors for participation were physician encouragement, accessibility, and patient awareness. Physicians most often expressed the need for longer consultation times (64.2%) and financial incentives (50.4%). Statistically significant associations were found between physician age, work experience, attitudes toward the program, and the applied incentive measures (p < 0.05).Conclusions: Family physicians in Lithuania have a positive attitude toward the CRC screening program, actively participate in its implementation, and assume responsibility for patient engagement. However, to enhance the program's effectiveness, additional organizational measures are necessary, such as incentive mechanisms and improved working conditions.