Entomological impact of three years of clothianidin-based indoor residual spraying in two high malaria endemic districts in Côte d’Ivoire

Clothianidin-based IRS was associated with a clear reduction in An. gambiae and An. coluzzii biting densities in the IRS districts and, more importantly, a significant reduction in EIR after accounting for changes over the same period in the neighbouring control areas. These findings are consistent with the epidemiological findings reported in the same sites and demonstrates the utility of IRS as an important tool for malaria control in a highly endemic setting like Côte d'Ivoire.