Effectiveness of pulmonary rehabilitation in bronchiectasis patients: comparing airway clearance device and physical activity

<bold>Introduction:</bold> Non-cystic fibrosis bronchiectasis (NCFB) is a chronic disease characterized by impaired mucociliary clearance and airway inflammation. Pulmonary Rehabilitation (PR), including physical activity and airway clearance techniques (ACTs), is crucial for management. Objects Evaluate the clinical utility of PR in an outpatient setting and compare the two PR techniques. <bold>Methods:</bold> A prospective randomized study was conducted on NCFB patients referred to our institute over 12 months. The patients were divided into three groups: the PR Group included 15 patients, 8 of whom performed daily ACT by Temporary Positive Expiratory Pressure (T-PEP) (T-PEP Group) and 7 performed physical activity 3 times a week (Exercise Group). The Control Group (13 patients) did not undergo PR. Functional (spirometry and 6MWT) and clinical (dyspnea, QoL, sputum purulence, exacerbations and hospitalizations) outcomes were collected at baseline (T0) and 12-month follow-up (T1). <bold>Results:</bold> 28 patients were enrolled. The PR Group showed significant improvements in outcomes over time (see Tab). No significant difference was found between the two PR groups. <bold>Conclusions:</bold> This preliminary study suggests that PR (physical activity and ACTs) improves long-term function and quality of life in NCFB patients. <fig><object-id>erj;66/suppl_69/PA4932/F1</object-id><object-id>F1</object-id><object-id>F1</object-id><graphic></graphic></fig>