Different degrees of expression of pulmonary fibrosis signs with intratracheal administration of bleomycin at different doses in male SD rats (a study aimed at helping to select the optimal bleomycin dose for modeling pulmonary fibrosis)

20250 citationsJournal Articlegold Open Access

Authors

Elena A. Tukhovskaya · Institute of Bioorganic Chemistry

Yulia A. Palikova · Institute of Bioorganic Chemistry

M. S. Severyukhina · Institute of Bioorganic Chemistry

Alina M. Ismailova · Institute of Bioorganic Chemistry

В. А. Паликов · Institute of Bioorganic Chemistry

Г. А. Слащева · Institute of Bioorganic Chemistry

N. A. Borozdina

Abstract

Results obtained in the study demonstrate a dose-dependent effect of BLM on the PF severity, which provides information that will help select BLM dose suitable for obtaining desired degree of PF in animal models.

Topics & Keywords

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Pneumonia and Respiratory Infections Cardiac Fibrosis and Remodeling

Publication Details

Published in: Frontiers in Pharmacology

Volume 16, pp. 1702991-1702991

DOI: 10.3389/fphar.2025.1702991

Field-Weighted Citation Impact: 0.00

Command Palette

Different degrees of expression of pulmonary fibrosis signs with intratracheal administration of bleomycin at different doses in male SD rats (a study aimed at helping to select the optimal bleomycin dose for modeling pulmonary fibrosis)

Authors

Abstract

Topics & Keywords

Publication Details