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"Psychedelic research - Going global" is a Special Issue of the Journal of Psychopharmacology that has been compiled and published as a tribute to Dr. Roland R Griffiths in recognition of his pioneering and pivotal contribution to the field of psychedelic research. Dr. Griffiths was Professor in the Departments of Psychiatry and Neurosciences at Johns Hopkins University School of Medicine, and latterly, the founding director of the Center for Psychedelic and Consciousness Research. It is not an exaggeration to state that his discoveries, indefatigable support and advocacy laid the foundations of the global revival of psychedelic research. The issue commences with a tribute written by many of Dr. Griffiths' scientific colleagues and friends. This homage summarises the fundamental contribution Dr. Griffiths made to research in many areas of neuropharmacology and psychiatry, in addition to his more recent published work on the neurobehavioural and therapeutic effects of the psychedelics. Other articles in this edition comprise a mix of commentaries, reviews, and original research and are divided under the headings of non-clinical, clinical, and strategic/regulatory. This Special Issue attracted contributions by experts from around the world, and as a compendium of knowledge, it is an invaluable resource that provides a clear perspective on the current status of research in the field. Dr. Griffiths was a scientist who maintained an open mind to ideas and knowledge from every source, and we are certain he would fully endorse the concept of Psychedelic research - Going global.