Dysbiosis‐Mediated Inflammation: A Pathophysiological Link Between Rheumatoid Arthritis and Periodontitis

20250 citationsJournal Articlehybrid Open Access

Authors

Isabel Lopez‐Oliva · Queen Mary University of London

Iain Chapple · Birmingham Community Healthcare NHS Trust

Akshay D. Paropkari · Kiko Labs (United States)

Shweta Saraswat · The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute

Praveen Sharma · Birmingham Community Healthcare NHS Trust

Stefan Serban · University of Leeds

Abstract

We demonstrate a mutualistic influence of RA and PD, beginning with RA-induced dysbiosis of the periodontal microbiome, progressing to periodontal inflammation and culminating in PD-driven exacerbation of systemic inflammation.

Topics & Keywords

Oral microbiology and periodontitis research Gut microbiota and health Rheumatoid Arthritis Research and Therapies

Publication Details

Published in: Journal Of Clinical Periodontology

Volume 53, Issue 3, pp. 466-477

DOI: 10.1111/jcpe.70063

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Dysbiosis‐Mediated Inflammation: A Pathophysiological Link Between Rheumatoid Arthritis and Periodontitis

Authors

Abstract

Topics & Keywords

Publication Details