L-arginine-induced chronic pancreatitis in mice: Evaluating effects of pirfenidone and simvastatin

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Authors

Rajiv Mehta · Yahoo (United Kingdom)

Archi Patel · Veer Narmad South Gujarat University

Bhavin Vyas · Hindu College of Pharmacy

Bhargavi V. Desai · Hindu College of Pharmacy

Dhvani Adhvaryu · Veer Narmad South Gujarat University

Prakash Sojitra · Activation Laboratories

Simple Bhuptani

Abstract

Combination of pirfenidone and simvastatin demonstrated a synergistic therapeutic effect in reducing inflammation, fibrosis, and oxidative stress in an L-arginine-induced chronic pancreatitis mouse model, suggesting promise for chronic pancreatitis management.

Topics & Keywords

Pancreatitis Pathology and Treatment Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Chemotherapy-induced organ toxicity mitigation

Publication Details

Published in: World Journal of Gastrointestinal Pharmacology and Therapeutics

Volume 16, Issue 4, pp. 111977-111977

DOI: 10.4292/wjgpt.v16.i4.111977

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L-arginine-induced chronic pancreatitis in mice: Evaluating effects of pirfenidone and simvastatin

Authors

Abstract

Topics & Keywords

Publication Details