Lumbar Medial Branch Cryoneurolysis Improves Pain and Function Versus Radiofrequency Ablation for Chronic Low Back Pain: 12-Month Randomized Pilot Study.

At 12 months after treatment for CLBP, cryoneurolysis had a favorable safety profile and led to more significant improvements in pain and functional disability than did RFA. A large multicenter trial is warranted to further investigate the effects of cryoneurolysis on CLBP.