Bacteria in RSV-infected children: A systematic review and meta-analysis in the context of recent microbiome research

The findings of this review highlight the substantial diversity of respiratory bacteria in RSV-infected children, with M. catarrhalis, H. influenzae, and S. pneumoniae being the most frequently detected species. Respiratory bacterial co-detection in RSV-infected children is associated with distinct clinical symptoms, radiological findings, specific biomarkers, increased disease severity, and higher healthcare resource use. These findings collectively emphasize the importance of integrating microbiome-preserving strategies, precision diagnostics, and innovative prevention and therapeutic measures to optimize care and outcomes for children with RSV-associated ARIs.