ENT1 inhibition enhances weight control and metabolic health in diet-induced obesity

20250 citationsJournal Articlegold Open Access

Authors

Lucas Martins Chaible · Bone Therapeutics

Julie Preillon · Bone Therapeutics

Charlotte Philippart · Bone Therapeutics

Alizée Canevat · Bone Therapeutics

Laura Saerens · Bone Therapeutics

Dimitri Kondratow · Bone Therapeutics

Michael Deligny ·

Abstract

EOS-518 promotes weight loss, improves metabolic parameters, restores adipose tissue function, and reduces inflammation in DIO mice. Altogether, this study positions ENT1 as a promising therapeutic target for the treatment of obesity and associated metabolic disorders.

Topics & Keywords

Regulation of Appetite and Obesity Adipokines, Inflammation, and Metabolic Diseases Adipose Tissue and Metabolism

Publication Details

Published in: Biomedicine & Pharmacotherapy

Volume 193, pp. 118848-118848

DOI: 10.1016/j.biopha.2025.118848

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ENT1 inhibition enhances weight control and metabolic health in diet-induced obesity

Authors

Abstract

Topics & Keywords

Publication Details