Gold-Catalyzed Reactions between 2-Alkenyl-1-arylalkynes and Nitrones via 1,2-C,N-Difunctionalizations Together with the C═C Double Bond Cleavage

This work reports gold-catalyzed novel 1,2-C,N-difunctionalizations of 2-alkenyl-1-arylalkynes with nitrones, along with the C═C double bond cleavage of substrates. Our mechanistic analysis suggests that gold directs an initial attack of <i>N</i>-hydroxyaniline on such enynes, followed by a cascade reaction with one nitrone molecule before the C═C double bond cleavage.