PancreaSeq Genomic Classifier (PancreaSeq GC) Improves Pancreatic Cyst Classification and Detection of Advanced Neoplasia: A Multi-institutional Validation Study

20250 citationsJournal Articlehybrid Open Access

Authors

Aatur D. Singhi · UPMC Health System

Abigail I. Wald · University of Pittsburgh Medical Center

Katelyn Smith · University of Pittsburgh Medical Center

Larissa Wolkenstein · University of Pittsburgh Medical Center

Robert Bubar · University of Pittsburgh Medical Center

Ricardo Díaz‐Aragon · University of Pittsburgh Medical Center

Maria Grupillo

Abstract

This validation study demonstrates statistically significant improvements in PancreaSeq GC for mucinous cysts and advanced neoplasia, establishing it as a clinically valuable tool for the preoperative evaluation of pancreatic cysts.

Topics & Keywords

Pancreatic and Hepatic Oncology Research Pancreatitis Pathology and Treatment Genetics, Bioinformatics, and Biomedical Research

Publication Details

Published in: Annals of Surgical Oncology

Volume 33, Issue 4, pp. 2865-2875

DOI: 10.1245/s10434-025-18848-8

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PancreaSeq Genomic Classifier (PancreaSeq GC) Improves Pancreatic Cyst Classification and Detection of Advanced Neoplasia: A Multi-institutional Validation Study

Authors

Abstract

Topics & Keywords

Publication Details