Ultrastaging Confirms the Superior Sensitivity of Quantitative Immunocytology for Detection of Lymph Node Spread in Non–Small Cell Lung Cancer Patients

Routine histopathologic workup underestimates LN spread in NSCLC patients and occasionally misses even macrometastases. US confirms and validates the significantly higher sensitivity of IC over routine histopathologic workup. In particular, IC has the potential to improve appropriate staging and prognostic stratification of patients in the future.