Nanopore based RNA methylation profiling of a circulating lung cancer biomarker

20250 citationsJournal Articlegold Open Access

Authors

Marta Sánchez-Delgado · Hummingbird Diagnostics (Germany)

Maurice Frank · Hummingbird Diagnostics (Germany)

Tomáš Šišmiš · Roosevelt Hospital

Mustafa Kahraman · Hummingbird Diagnostics (Germany)

Alberto Daniel-Moreno · Hummingbird Diagnostics (Germany)

Emmika Mummery · Hummingbird Diagnostics (Germany)

Jessika Ceiler

Abstract

This approach enables direct, single-molecule methylation profiling of small RNAs in blood and identifies a lung cancer-associated methylation pattern with diagnostic potential. It is readily compatible with multi-modal liquid biopsy assays to enhance performance.

Topics & Keywords

Nanopore and Nanochannel Transport Studies Advanced Electron Microscopy Techniques and Applications Microfluidic and Capillary Electrophoresis Applications

Publication Details

Published in: Communications Medicine

Volume 5, Issue 1, pp. 521-521

DOI: 10.1038/s43856-025-01235-5

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Nanopore based RNA methylation profiling of a circulating lung cancer biomarker

Authors

Abstract

Topics & Keywords

Publication Details