LAMC2 promotes gallbladder carcinoma metastasis through the TGF-β pathway

20250 citationsJournal Articlegold Open Access

Authors

Mengyou Xu · Peking University Cancer Hospital

Yuanyuan Zhang · Eastern Hepatobiliary Surgery Hospital

Hailan Feng · Peking University Cancer Hospital

Taiyu Shang · Fudan University Shanghai Cancer Center

Yibin Chen

Erdong Liu · Fudan University

Yun‐Kai Lin · Second Military Medical University

Abstract

Our findings suggest that LAMC2 promotes GBC progression and metastasis, potentially by regulating the TGF-β signaling pathway. Therefore, LAMC2 could serve as a potential prognostic biomarker and therapeutic target for GBC.

Topics & Keywords

Cholangiocarcinoma and Gallbladder Cancer Studies Cell Adhesion Molecules Research TGF-β signaling in diseases

Publication Details

Published in: Cancer Cell International

Volume 26, Issue 1, pp. 25-25

DOI: 10.1186/s12935-025-04123-z

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LAMC2 promotes gallbladder carcinoma metastasis through the TGF-β pathway

Authors

Abstract

Topics & Keywords

Publication Details