Cavβ dances the two-step with VSD II

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Authors

Ben Short · Rockefeller University Press

Abstract

JGP study (De Giorgis et al. https://doi.org/10.1084/jgp.202413739) reveals that the auxiliary Cavβ3 subunit regulates the cardiac calcium channel Cav1.2 by modulating the two-step activation of VSD II.

Topics & Keywords

Ion channel regulation and function Congenital heart defects research Cardiac electrophysiology and arrhythmias

Publication Details

Published in: The Journal of General Physiology

Volume 158, Issue 1

DOI: 10.1085/jgp.202513935

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Cavβ dances the two-step with VSD II

Authors

Abstract

Topics & Keywords

Publication Details