FluoroPerm 151 extended wear: a clinical study.

In this 3-month study, 132 (81.5%) of 162 eyes (81 subjects) successfully wore FluoroPerm 151 RGP lenses on an extended wear schedule. Fifty-nine (72.8%) subjects were adapted RGP lens wearers; 3 (3.7%) were polymethylmethacrylate (PMMA) lens wearers; 12 (14.8%) were current hydrogel lens wearers; and 7 (8.6%) had no previous contact lens experience. Throughout the study, no significant physiologic or pathologic concerns were found or led to lens discontinuation. Among the 30 eyes that discontinued the study, there were no serious health concerns; the chief reason for discontinuing lens wear was discomfort. Study results seemed to indicate that little, if any, physiologic stress was induced by extended wear of the FluoroPerm 151 lenses. The overall clinical success with the FluroPerm 151 lenses can be attributed to the material's high level of oxygen flux and compatible surface characteristics.