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Abstract Title Non-Surgical Management of a Partial ACL Tear with Platelet-Rich Plasma: A Case Report Background Anterior cruciate ligament (ACL) injuries are common in pivoting sports and often result in long-term functional limitations. While complete ACL tears typically require surgical intervention, partial tears in active individuals may benefit from biologic therapies. We present a case of a recreational athlete with a partial ACL tear managed successfully with platelet-rich plasma (PRP) therapy. Methods A 29-year-old male recreational basketball player presented with acute right knee pain after landing awkwardly from a jump. He reported a mild "pop" sensation, immediate swelling, and difficulty bearing weight. He had no prior history of major knee injury. Initial conservative management included RICE and NSAIDs. Due to persistent pain and instability after 3 weeks, he was referred for further evaluation. Results Physical examination revealed mild effusion, tenderness along the medial joint line, and mild limitations in flexion and extension. Lachman test was mildly positive; anterior drawer test showed minimal translation. MRI demonstrated a partial tear of the ACL involving approximately 50% of the ligament fibers, with intact menisci and collateral ligaments. No chondral defects were noted. Given the partial nature of the injury and the patient's desire to avoid surgery, PRP therapy was recommended. The patient received two ultrasound-guided intra-ligamentous PRP injections over a four-week interval. Conclusion At the 3-month follow-up, the patient reported significant improvement in knee stability and function, with minimal pain. MRI demonstrated improved fiber continuity and decreased signal intensity in the ACL region. By 4 months post-injection, the patient had resumed non-contact basketball activity and continued with progressive strengthening and proprioception training. This case highlights the potential role of PRP therapy as a non-surgical treatment option in partial ACL tears, particularly in motivated patients seeking to return to activity. Further research is needed to better define indications and long-term outcomes of biologic therapies in ligamentous injuries.