Digital Intervention (MiVacunaLA 2.0) to Promote COVID-19 Vaccine Acceptance Among Hispanic Children: Community-Based Randomized Controlled Trial

MiVacunaLA demonstrates that a culturally tailored, community-based, mobile phone-delivered vaccine educational intervention can increase COVID-19 vaccine uptake among Hispanic children and improve caregivers' trust in governmental vaccine processes. MiVacunaLA is innovative in its integration of community-informed design with a fully automated, mobile phone-centric format and builds on prior literature by prospectively evaluating a culturally tailored, SMS text messaging-linked web curriculum in a community setting. Findings provide evidence that scalable, low-cost, digital strategies can measurably improve trust and uptake in a population facing persistent vaccination gaps. Real-world implications include the portability and adaptability of this approach across diverse communities and settings to support timely, community-engaged vaccination efforts for broader applicability and scalability in public health.