Environmental Health Language Collective (EHLC) Adverse Outcome Pathway (AOP) Standards Workshop Report

● A workshop was organized to promote collaboration between the international AOP community and the US-based biomedical knowledgebase and ontology communities and to promote FAIR (Findable, Accessible, Interoperable, and Re-Useable) data standards of AOPs. ● Coordination of relevant research that contributes to improved AOP data standards was discussed at a virtual, two-day l workshop hosted in June 2025 by the Environmental Health Language Collaborative (EHLC). ● A diverse set of scientists and stakeholders participated in the two-day workshop. ● Approaches to improved AOP data integration, interoperability, and mechanistic insight, as well as data resources and tools, were discussed in light of their benefit to AOP development and improved FAIR AOP data standards. ● Recommendations and next steps for improvements to the mapping of biomedical data to AOPs in the AOP-Wiki are presented herein.