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The deliverable, D2.1 “Analysis of the Spatial and Ecosystem Characteristics of the Textile and Clothing Sectors in Rotterdam and Athens” (intermediate version), forms a core research foundation of the FABRIX project. Its main aim is to understand the spatial dynamics and network needs of the textile and clothing (T&C) sector in both cities, providing a baseline snapshot of current conditions and informing the future development of the FABRIX platform. The spatial analysis addresses the question of where textile and clothing activities take place, what we term the spaces of networks. Using detailed business-level data, the deliverable visualizes the location of businesses across the T&C value chain to identify key hotspots and emerging areas of activity. In Athens, spatial patterns remain concentrated in traditional commercial districts such as Omonia and Psiri, while more boutique or youth-driven activity is emerging in neighbourhoods such as Kolonaki and Kypseli. Distribution is shaped by affordability, historical land use, and access to labour. In Rotterdam, by contrast, textile activity has shifted significantly over time. Once concentrated in the city centre, activity has become more diffused, with new clusters forming in neighbourhoods such as Zwaanshals and Oude Noorden, particularly for design, education, and circular practices. This decentralization reflects broader urban transitions, policy efforts, and the growing role of circular economy initiatives. Beyond spatial patterns, FABRIX also examines the networks of spaces, or the relationships and dynamics that underpin ecosystem functioning. Through semi-structured interviews with businesses, facilitators, and government actors in both cities, the deliverable explores the operational realities, opportunities, and systemic barriers facing those driving circular and regenerative practices in the T&C sector. Across both cities, businesses are experimenting with upcycling, take-back schemes, local production, and circular design, often driven by founders with a strong personal motivation to reform the T&C system. However, support systems remain fragmented. Long-term partnerships are rare, sourcing materials is often informal, and impact measurement is still underdeveloped. Facilitators play a vital role in both ecosystems, acting as connectors across value chains. However, they face significant challenges related to maintaining networks, managing data, and scaling efforts, especially in the face of limited funding or short-term projects. In Rotterdam, a notable finding is that entrepreneurs themselves often adopt facilitation roles, blurring the boundaries between business and ecosystem support, which is a reality that the FABRIX platform must take into account in its user design. Policymakers in both cities recognize the potential of the circular T&C transition, but also the complexity involved. In Rotterdam, the Rotterdam Circulair program is particularly active in supporting behavioural change, waste management, and local production. However, challenges remain around data collection, spatial planning, and cross-departmental coordination. Together, the quantitative spatial mapping and qualitative ecosystem analysis offer an integrated picture of where and how FABRIX can make a difference. With creativity, passion, and a shared vision for sustainable transformation present in both cities, the FABRIX platform is well-positioned to respond to the spatial and relational needs identified in this study. If designed with flexibility, sensitivity to place-based contexts, and long-term custodianship in mind, FABRIX has the potential to support the transition from isolated initiatives to connected, resilient, and scalable circular ecosystems. The structure of the deliverable is as follows: Chapter 2 provides the introduction, outlining the deliverable’s objectives, scope, and connection to the broader FABRIX project. Chapter 3 presents the methodological approach, detailing the spatial analysis methods and qualitative interview design. Chapters 4 and 5 focus on the two case study cities, Athens and Rotterdam, respectively, offering detailed accounts of the history of their urban industrial transitions, spatial patterns of T&C business activity, and insights from interviews with businesses, facilitators, and policymakers. Chapter 6 concludes the deliverable with a synthesis of key findings and final reflections.