Cost-Utility Analysis of Renal Replacement Therapy Modalities in the Management of Severe Acute Kidney Injury in US Critically Ill Patients

CRRT is likely a cost-effective option for managing severe AKI in the ICU compared with IHD. This study builds on existing economic evaluations by incorporating large comparative studies and exploring clinical uncertainty. The model highlights the need to clarify RRT's role in CKD progression and enhance post-AKI care to improve patient outcomes.