Association between glucagon‐like peptide‐1 receptor agonists and risk of dementia in older adults with type 2 diabetes: A target trial emulation

20251 citationsJournal Articlehybrid Open Access

Authors

Ting Zhou · Science History Institute

HUILIN TANG · Science History Institute

Bingyu Zhang · University of the Sciences

Dazheng Zhang · Science History Institute

Yiwen Lu · University of the Sciences

Lu Li · University of the Sciences

Jiajie Chen ·

Abstract

In this large real-world cohort, GLP-1 RAs were associated with lower dementia risk than DPP4is but higher risk than SGLT2is. Prospective, biomarker-informed studies are needed to clarify mechanisms and inform treatment choices in older adults with T2D.

Topics & Keywords

Diabetes Treatment and Management Bariatric Surgery and Outcomes Heart Failure Treatment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Diabetes Obesity and Metabolism

Volume 28, Issue 3, pp. 1984-1996

DOI: 10.1111/dom.70384

Field-Weighted Citation Impact: 1.26