The conceptions of mechanism of effect of blood as universal medication in xix century

The article is devoted to consideration of changes in conceptions about physiological mechanism of effect of donor blood as medication in the XIX century. The relationship between changes of physiological knowledge about properties and functions of blood and modification of whole and defibrinated blood preparations applied for transfusion is demonstrated. The temporary transition from using blood to salt blood substitutes at the end of the XIX century is justified. The studies of liquid tissue - blood - in the XIX century became scientific base for fundamental discoveries in the early XX century. The relationship between evolution of conceptions about mechanism of action, modes of preparation and methods of administration of donor blood throughout the XIX century was established.