Posterior Reversible Encephalopathy Syndrome (PRES) in a ten-year old child with invasive meningococcal disease

Invasive meningococcal disease is not uncommon in paediatric practice, however, association with Posterior Reversible Encephalopathy Syndrome (PRES) is a rarely been reported. Mortality of invasive disease is high for multi-organ failure if any delay in diagnosis and urgent comprehensive treatment along with high level critical care support with invasive haemodynamic monitoring. Neurological sequelae are sometimes unavoidable for multiple reasons and it is to be aware of those with high risk groups. This is Ma EPW, a 10-year-old girl with 3 days high spiking temperature followed by status epilepticus and circulatory collapse. Noticeably, she expressed widespread non-blanchable purpura. She has been treated with oral prednisolone for 2 months after diagnosed as nephrotic syndrome but she did not achieved remission yet. In summary, defining invasive meningococcal disease requires clinical as well as laboratory support. If resource constraints are huge, probable invasive disease demands urgent clinical attention and critical care support.