Quantitative Systems Pharmacology Models of Anti‐Amyloid Treatments for Alzheimer’s Disease: A Systematic Review

20250 citationsJournal Articlehybrid Open Access

Authors

Lara Herriott · University of Oxford

Mark Coles · University of Oxford

Eamonn A. Gaffney · University of Oxford

Nicolas Fournier · AC Immune (Switzerland)

Nicolas Sanchez · AC Immune (Switzerland)

Olivier Sol · AC Immune (Switzerland)

Marija Vukicevic ·

Abstract

The assessment of nine QSP models provided a useful context to inform ongoing QSP model development and refinement efforts, such that future models may better inform therapeutic strategies for the treatment of AD. In particular, enhanced focus on quality issues will serve to improve the utility of future QSP models.

Topics & Keywords

Alzheimer's disease research and treatments Statistical Methods in Clinical Trials Computational Drug Discovery Methods

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Alzheimer s & Dementia

Volume 21, Issue S5, pp. e102996-e102996

DOI: 10.1002/alz70859_102996

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