Can You Properly Manage Delusional Parasitosis?

Delusional parasitosis is a psychiatric disorder in which one experiences persistent, false delusions of being infected by parasites or other organisms. Symptoms include formication, pruritis, and self-inflicted cutaneous manifestations. In this article, we discuss the complicated case of a 45-year-old male patient with history of Crohn's disease, opioid use disorder, and post-traumatic stress disorder to highlight key concepts of the disease. The clinical presentation often leads to a broad differential diagnosis, which can complicate and delay treatment.