Associations Between Genetic Polymorphisms and Psychological Variables in Women With Fibromyalgia: A Cross‐Sectional Study

20251 citationsJournal Articlehybrid Open Access

Authors

Víctor Riquelme‐Aguado · Universidad Rey Juan Carlos

María Elena González‐Álvarez · Universidad Rey Juan Carlos

Silvia Di‐Bonaventura · Universidad Rey Juan Carlos

Leonardo Rodríguez‐Lagos · Universidad Rey Juan Carlos

Alazne Zabarte del Campo · Universidad Rey Juan Carlos

Francisco Gómez‐Esquer · Universidad Rey Juan Carlos

Gema Díaz‐Gil

Abstract

Genetic variability influences psychological vulnerability in fibromyalgia. Specific variants were associated with key psychological traits: BDNF rs6265 with pain catastrophising, OPRM1 rs1799971 with anxiety, and MAOA rs1137070 with depressive symptoms. These findings reveal an interplay between genetic and psychological factors that may guide more personalised strategies for managing fibromyalgia.

Topics & Keywords

Fibromyalgia and Chronic Fatigue Syndrome Research Pain Mechanisms and Treatments Psychosomatic Disorders and Their Treatments

UN Sustainable Development Goals

Gender equality

Publication Details

Published in: European Journal of Pain

Volume 30, Issue 1, pp. e70201-e70201

DOI: 10.1002/ejp.70201

Field-Weighted Citation Impact: 1.55