Unfractionated Heparin Dosing in Pediatric Venoarterial Extracorporeal Membrane Oxygenation: Single-Center Retrospective Study, 2015–2021

20251 citationsJournal Article

Authors

Noémie de Cacqueray · Hôpital Necker-Enfants Malades

Frantz Foissac · Inserm

Naim Bouazza · Inserm

Domitille Gontharet · Hôpital Necker-Enfants Malades

Delphine Borgel · Hôpital Necker-Enfants Malades

Margaux Pontailler · Hôpital Necker-Enfants Malades

Olivier Raisky ·

Abstract

In children undergoing VA-ECMO, body weight, and time-varying clearance explained the variability for UFH between subjects. This model can be used to optimize initial UFH dosing.

Topics & Keywords

Mechanical Circulatory Support Devices Antibiotics Pharmacokinetics and Efficacy Heparin-Induced Thrombocytopenia and Thrombosis

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Pediatric Critical Care Medicine

Volume 27, Issue 3, pp. 244-252

DOI: 10.1097/pcc.0000000000003887

Field-Weighted Citation Impact: 0.76