Kremen2 Promotes Colorectal Cancer Progression by Activating the EGFR/JAK2/STAT3 Signaling Pathway.

20260 citationsJournal Articlegreen Open Access

Authors

Xiaopei Xue · Centro Hospitalar do Baixo Vouga

Sumei Zhang · Centro Hospitalar do Baixo Vouga

Xu Sun · Centro Hospitalar do Baixo Vouga

Abstract

Kremen2 promotes colorectal cancer cell proliferation and migration through activation of the EGFR/JAK2/STAT3 pathway. These findings identify Kremen2 as a potential therapeutic target in CRC.

Topics & Keywords

Cytokine Signaling Pathways and Interactions Pharmacological Effects of Medicinal Plants Protein Tyrosine Phosphatases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 24, Issue 1, pp. e4234-e4234

DOI: 10.30498/ijb.2025.547463.4234

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