Safety of Exogenous Recombinant Human Platelet‐Derived Growth Factor‐ <scp>BB</scp> ( <scp>rhPDGF</scp> ‐ <scp>BB</scp> ) for Medical and Cosmetic Applications: A Review

The totality of the data demonstrates that the use of rhPDGF-BB for regeneration and rejuvenation of skin and other tissues has an excellent safety profile, a finding further affirmed by its record of safe and effective use in multiple medical indications for over 25 years.