<scp>ACMG</scp> / <scp>AMP</scp> ‐Based Variant Classification of a Novel <scp> <i>HBA2</i> </scp> Variant ( <scp> <i>HBA2</i> </scp> : C.297del, Hb Taiping) in Compound Heterozygosity With Hb Adana ( <scp> <i>HBA2</i> </scp> :C. <scp>179G</scp> &gt;A) Causing Non‐Deletional Hb H Disease

This study identifies and characterises a novel α-globin gene variant, Hb Taiping, in a Malay family with α-thalassaemia. The discovery contributes to the growing body of pathogenic mutations linked to α-thalassaemia and underscores the importance of precise variant classification for effective diagnosis, risk assessment, and genetic counselling.