Copy-Number Profiling and Methylation-Based Tumor Typing during Prenatal Cell-Free DNA Screening

20250 citationsJournal Articlegreen Open Access

Authors

Stefania Tuveri · Center for Human Genetics

Tatjana Jatsenko · Center for Human Genetics

Dhanya Sudhakaran · Center for Human Genetics

Qiang Fu · Center for Human Genetics

Antoine Passemiers · KU Leuven

Angelica Pagliazzi · Center for Human Genetics

Kris Van Den Bogaert ·

Abstract

Methylome and aneuploidy-aware cfDNA screening could substantially improve the diagnostic processes, pinpoint the origins of aneuploidy and improve cancer management during pregnancy.

Topics & Keywords

Prenatal Screening and Diagnostics Gestational Trophoblastic Disease Studies Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 72, Issue 3, pp. 367-380

DOI: 10.1093/clinchem/hvaf167

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