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The realization of the Topological-Entropic Theory with Conformal Vacuum Tensor Lattice (TET--CVTL) in laboratory settings hinges on materials capable of sustaining ultraclean turbulence (Re → ∞), eternal anyonic braiding, and topological protection under extreme conditions. This preprint systematically evaluates three leading candidates that bridge primordial knot saturation to practical applications in aneutronic fusion, vacuum torque devices, and analog cosmological simulations.Graphene encapsulated in hexagonal boron nitride (hBN) heterostructures offers room-temperature ultraclean hydrodynamic electron flow with effective viscosity approaching zero, enabling persistent anyonic braiding and collective phase enhancement in dense systems. Superfluid helium-4 (He-II) below the lambda point provides exactly zero dissipation in the superfluid component, serving as a direct analog of de Sitter spacetime and eternal vortex lattices. Chemical vapor deposition (CVD) diamond delivers unmatched structural robustness, thermal conductivity, and radiation hardness for containment in high-intensity experiments.A detailed comparison table highlights the complementary strengths of these materials, while proposed experimental configurations — including laser-plasma on boron targets with hBN substrates, optical manipulation of quantized vortices in He-II, and diamond anvil cells with embedded graphene devices — provide concrete pathways for realizing TET--CVTL phenomena.These materials collectively enable the transition from theoretical primordial trefoil saturation to experimental manifestation, paving the way for topological catalysis of p-¹¹B aneutronic fusion and precision tests of emergent cosmic geometry in controlled environments. Tetcollective.org