Afferent Renal Nerves Drive Sympathoexcitation and Hypertensive Heart Failure

20260 citationsJournal Article

Authors

Shota Ikeda · Kyushu University

K Shinohara · Kyushu University

Yoshiyasu Ono · Kyushu University

Hiroka Nakashima · Kyushu University

Ryohei Miyamoto · Kyushu University

Ayano Hara · Kyushu University

Soichiro Kashihara · Kyushu University

Abstract

Afferent renal nerve input activates the sympathetic nervous system before left ventricular systolic dysfunction and contributes to hypertensive HF, with PVN vasopressin driving this sympathoexcitation.

Topics & Keywords

Renin-Angiotensin System Studies Heart Failure Treatment and Management Neuroscience of respiration and sleep

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hypertension

Volume 83, Issue 3, pp. e25247-e25247

DOI: 10.1161/hypertensionaha.125.25247

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