A novel, experimental design to assess rapid antidepressant action: Results from a phase 1b randomized trial of NV-5138

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Authors

Andrea E. Formella · Supernus Pharmaceuticals (United States)

Gianpiera Ceresoli-Borroni · Supernus Pharmaceuticals (United States)

Abstract

The innovative design of this exploratory study facilitated appropriate participant selection and rapid antidepressant response detection. These features may be useful in other trials evaluating RAADs (ClinicalTrials.gov, NCT03606395).

Topics & Keywords

Treatment of Major Depression Neurotransmitter Receptor Influence on Behavior Digital Mental Health Interventions

Publication Details

Published in: Journal of Psychiatric Research

Volume 194, pp. 211-220

DOI: 10.1016/j.jpsychires.2026.01.006

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A novel, experimental design to assess rapid antidepressant action: Results from a phase 1b randomized trial of NV-5138

Authors

Abstract

Topics & Keywords

Publication Details