Clusters in Thalamic iEEG Spectral Features Reveal Sleep/Wake Differences Over Time

These results suggest that thalamic iEEG data can potentially be used to identify wake/sleep states electrographically without traditional sleep studies. This could enable state-dependent neuromodulation therapy. The observed changes in sleep/wake clusters over time could represent neuromodulation-driven changes in thalamocortical networks and warrant further investigation.