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Maternal health and nutritional Information form the cradle of healthy genetic development and population health, safeguarding the right to life and the quality of future livelihoods. Thus, this health and nutrition information often enables most females of reproductive age 15 to 49 years, globally, regionally and locally in western Kenya, to access quality, affordable and reliable health education on maternal health care and nutrition, and to mediate a primordial prevention and reduce maternal disease burden rates. It also promotes health demography and human development, through prevention and protection missions of public health, via community health awareness and capacity building, empowering population health and promote a healthy population. This is achieved by enabling regular health education on maternal and child nutrition, for better primary prevention than cure among rural females of the reproductive age and the larger population health through synergistic community participation. It was these reasons that led to the study, which aimed to evaluate the factors influencing increased accessibility to maternal and nutritional health information and their effects on reproductive health practices among rural females of reproductive age (15–49 years) in Western Kenya. Specifically, the study focuses on determining the prevalence of population health in the accessibility to affordable maternal health and balanced diet nutrition practices, determining the level of community participation in the promotion on maternal child health nutritional health education/information for quality primordial prevention and decrease of maternal child health and nutrition, and lastly assessing how social economic, social cultural and religious beliefs influence the increased accessibility of maternal child health and nutrition health information on maternal health nutrition practices among rural females of the reproductive age in Western Kenya. The study also aimed to achieve in global health goals number 3 and 17 of Vision 2030 and beyond, in global health. Over 80% of community households have limited access to efficient, affordable, reliable, and sustainable quality maternal child health and nutrition information to promote primordial prevention in the general basic health population, especially in Sub Saharan Africa (SSA), through capacity building of health service providers and community health workers (CHWs), as their main sources of accessibility of maternal child health information, in the large diversified society of demographic health population and development, to improve the health population of the population health and their health live hoods. The study exploited descriptive, cross-sectional, cohort and triangulation designs. Purposive clusters, census retrospective and prospective sampling techniques were used to explore the ante and postnatal mothers with children aged 0-24 months as the target population. The questionnaire used as tool of survey and key informant interview and focused group discussion (FGD) was used in interview guides. Data was managed by SPSS version 27 and analysed by cross-tabulation of descriptive and inferential statistics to provide a significant inference. Results showed that health service providers and community health workers were the main sources of providing quality health education/information 97 (46.2%) and 69 (32.9%) respectively, with significant support from the global health of RR (0. 463, 0.335). The prevalence of the increased accessibility of maternal health nutrition was health/education information 101 (48%). Community awareness on the uptake of balance dietary intake from both animal proteins and plant was 67%, and majority opined significant uptake of animal protein was determined by social cultural with P value of 0.025, 95 % CI, and social economic has an influence remain insignificant with OD 1.0 and RR (0.25, 0.345), due to existing synergistic public private partnership global health to decrease unmated needs in the inequality at maternal health and nutrition community households. Need to advocate for more global health in public-private partnership participation to mediate the unmet basic needs of maternal health, nutrition and need to partner with urban reproductive of reproductive in issues of maternal health and nutrition, mediate global maternal health and nutrition global health goals number 3 and 17 of Vision 2030 and beyond to sustain quality global livelihoods and population health development.