A Case-Control Study On Corpus Callosum Volume and ClinicalCorrelates in Treatment-Resistant and Responsive Schizophrenia Patients:Addressing MRI Analysis within Single-Subject and a Novel ArtificialIntelligence Paradigm

TRS is associated with pronounced neurological, cognitive, and clinical dysfunctions. Aberrant CC volume may contribute to TRS pathogenesis and executive function deficits. MRI-AI provides a robust, single-subject approach for characterizing CC abnormalities in schizophrenia, of-fering potential for personalized clinical assessment.