The Utility of Mucin 2 and Caudal-Type Homeobox Transcription Factor 2 Expression in the Diagnosis of Barrett's Esophagus: A Community-Based Study of Wide-Area Transepithelial Sampling and Forceps Biopsies

20260 citationsJournal Article

Authors

Nicholas J. Shaheen · University of North Carolina at Chapel Hill

F. Scott Corbett · Florida Digestive Health Specialists

Mendel E. Singer · Case Western Reserve University

William J. Salyers · University of Kansas

Sachin Srinivasan · University of Kansas

Vivek Kaul · University of Rochester

Arvind J. Trindade

Abstract

MUC2 immunohistochemistry may be more sensitive and specific for diagnosing BE than goblet cells by FB. FB misses approximately half of BE when using MUC2/WATS3D as an alternative gold standard. The addition of MUC2 immunohistochemistry may aid in the recognition of BE.

Topics & Keywords

Esophageal Cancer Research and Treatment Esophageal and GI Pathology Gastroesophageal reflux and treatments

Publication Details

Published in: The American Journal of Gastroenterology

DOI: 10.14309/ajg.0000000000003904

Field-Weighted Citation Impact: 0.00

Command Palette

The Utility of Mucin 2 and Caudal-Type Homeobox Transcription Factor 2 Expression in the Diagnosis of Barrett's Esophagus: A Community-Based Study of Wide-Area Transepithelial Sampling and Forceps Biopsies

Authors

Abstract

Topics & Keywords

Publication Details