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Objective : to determine the effects of different doses of an adsorbent on the state of interstitial metabolism in broilers when administered as part of complete feed. Materials and Methods . Two hundred day-old Isa Hubbard F15 meat chickens were selected for the study. Four groups (50 birds each) were formed using the analog group principle. To ensure experimental integrity, NaNO3 (sodium nitrate) was added to the feed formulation used for the test birds at a rate of 40 g/t of feed to ensure subtoxic levels of these compounds. Three experimental groups were administered the adsorbent: Group 1—1 kg/t; Group 2—1,5 kg/t; and Group 3—2 kg/t. The adsorbent was not administered to the control group. During the experiment, the test birds were reared for 42 days, after which they were individually slaughtered. Blood samples were collected for biochemical and morphological parameters. Results . The results demonstrate that, to optimize interstitial metabolism in broilers through more successful denitrification, it is advisable to add a feed adsorption agent at a dosage of 1,5 kg/t of feed to their feed with subtoxic nitrate levels. Thus, due to improved elimination of the studied toxins in blood samples, the birds in this group, compared to the control group, showed a 43,40 % decrease in methemoglobin concentration (P>0,95), while simultaneously increasing red blood cell count by 0,72×1012/L (P>0,95) and hemoglobin by 6,76 g/L (P>0,95). Protein, carbohydrate, and lipid metabolism also improved. There was a decrease in the mass fraction of nitrates by 2,26 times (P>0,95) and nitrites by 2,09 % times (P> 0,95).