The trials of insurance-based Data to Care-Rx: Low enrollment in the Antiretroviral Improvement among Medicaid enrolleeS (AIMS) study

Reasons for low patient-participant enrollment may include phone-based recruitment approach; lengthy identity verification and consent procedures; and lack of participant compensation. While we aimed to identify people with HIV without a current ART prescription refill, several participants reported having their medications available; this discrepancy suggests issues with unexpected participant behavior (e.g., stockpiling) or timeliness and accuracy of prescription claims data. Future insurance-based D2C-Rx interventions should account for these challenges, be tailored to context, and be nimble enough to pivot to alternative recruitment methods when needed.