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<i>Background:</i> Climate change-related events such as floods, droughts, and wildfires have been shown to affect global mental health. As climate change worsens, extreme weather events increase, leading to more climate-related mental health disorders globally. <i>Objective:</i> This review article assesses the impact of mental health and climate change in Africa to identify trends, research gaps, and potential interventions. <i>Methods:</i> A scoping review methodology, in accordance with the PRISMA-ScR guidelines, was employed. A search strategy was developed using MeSH and synonym terms to search PubMed, Web of Science, and African Journal Online databases from January 2000 to April 2025. A total of 2332 titles and abstracts were screened. <i>Results:</i> Sixteen articles were included in our final analysis. The studies included were conducted in three East African countries, three North African countries, two West African countries, two Central African countries, and one Southern African country. They were published between 2015 and 2024. Most (56%; <i>n</i> = 9) of the studies were cross-sectional studies. Climate change-related events, such as flooding, drought, and sea-level rise, have been found to affect mental health outcomes in countries like Ghana, Namibia, Nigeria, and Kenya. Commonly cited mental health outcomes included higher anxiety levels and lower well-being among relocated individuals, persistent stress and anxiety due to flooding in Ghana, and significant post-traumatic stress disorder symptoms among schoolchildren in Namibia. Vulnerable populations like children, adolescents, women, climate migrants, people living with HIV, and rural populations were found to be most impacted by climate change-related events. <i>Conclusion:</i> While this review highlights an increasing trend in the impact of climate change on the mental health of individuals in Africa, more studies are necessary to establish the relationship between mental health and climate change, and to develop interventions and policies that address the growing mental health burden resulting from climate change.