Cryoablation: A Minimally Invasive Alternative for Early-Stage Breast Cancer: 6-Year Outcomes of the FROST Clinical Trial

20260 citationsJournal Articlehybrid Open Access

Authors

D. R. Holmes · Beverly Hills Cancer Center

S. Manoian · Adventist Health Glendale

R. Layeequr Rahman · Texas Tech University

R. C. Ward · Brown University

N. Z. Carp · Lankenau Medical Center

M. Plaza · Virginia Oncology Associates

K. Kozlowski

Abstract

The FROST trial adds to the growing body of literature supporting the efficacy and safety of cryoablation and supports ongoing research on cryoablation as a strategy for de-escalating breast cancer therapy.

Topics & Keywords

Ultrasound and Hyperthermia Applications Thyroid Cancer Diagnosis and Treatment Breast Lesions and Carcinomas

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Surgical Oncology

Volume 33, Issue 4, pp. 3374-3382

DOI: 10.1245/s10434-025-18991-2

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